Useful Uses:
Increases sexual desire
Sustain an erection
Stronger ejaculations
Improves ability to achieve sexual satisfaction
The medicinal part of yohimbe is the bark. This evergreen tree grows up to 30 m in height. The bark is gray-brown and the inner fracture is reddish brown and grooved. It tastes bitter and the plant is odorless. The tree grows in the jungles of West Africa, Cameroon, Congo and Gabon. The main alkaloid present in the bark is Yohimbine.
Pharmacology
Yohimbe is a potent alpha-2 adrenoceptor blocker and a week alpha-1 adrenergic antagonist with some antidopaminergic properties. Yohimbe interacts with adrenoceptors that are selectively stimulated by clonidine, alpha- methylnorepinephrine, tramazoline, guanabenz, guanfacin. It also interacts with compounds that are nonselectively stimulated by norepinephrine and epinephrine. Yohimbe has a modest beneficial effect in the management of erectile dysfunction. Because of the alpha-2 adrenergic blockade, the drug is an effective treatment for sexual disorders such as decreased libido and sexual response, caused by selective serotonin reuptake inhibitors.
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